Do standards exist for exposure to vinyl chloride? Studies in workers who inhale vinyl chloride over many years show an increased risk of … Polyvinyl chloride, also known as PVC or vinyl, is arguably one of the most toxic types of plastic in our lives. Primary exposure to vinyl chloride occurs through inhalation. September 2015 Vinyl Chloride What is vinyl chloride? Prolonged exposure can cause cancer in the liver, brain, blood and lungs. Final AEGLs for Vinyl chloride (75-01-4) Exposure Period AEGL-1 AEGL-2 AEGL-3; 10 minutes: 450 ppm : 2800 ppm : 12000 ppm : 30 minutes: 310 ppm : 1600 ppm : 6800 ppm : 60 minutes: 250 ppm : 1200 ppm : 4800 ppm : 4 hours: 140 ppm : 820 ppm : 3400 ppm : 8 hours: 70 ppm : 820 ppm : 3400 ppm Acute (short-term) exposure to high levels of vinyl chloride in air has resulted in central nervous system (CNS) effects, such as … If vinyl chloride is detected in your water, contact your local or state health department. Vinyl chloride is classified as Group 1 carcinogen by the IARC, meaning it is seen as a definite cause of cancer in humans. Portal hypertension, liver fibrosis, and angiosarcoma of the liver (ASL) have been reported among workers exposed to vinyl chloride monomer (VCM) since the 1970s. Occupational exposure to vinyl chloride may occur in those workers concerned with the production, use, transport, storage, and disposal of the chemical. Sloane K. Tilley, Rebecca C. Fry, in Systems Biology in Toxicology and Environmental Health, 2015. (1,2) Assessing Personal Exposure Vinyl chloride can be detected in urine and body tissues, but the tests are not reliable indicators of total exposure. Angiosarcoma attacks the lining of blood vessels, and can occur in any area of the body. (1,2) The U.S. Environmental Protection Agency has set a maximum contaminant level of 2 ppb of vinyl chloride for public drinking water supplies. PREFACE. Most vinyl chloride is used to make polyvinyl chloride (PVC) plastic and vinyl products. A statement of each employee's suitability for continued exposure to vinyl chloride including use of protective equipment and respirators, shall be obtained from the examining physician promptly after any examination. It is not stable at high temperatures. A copy of the physician's statement shall be provided each employee. In 2007, the International Agency for Research on Cancer established the association of VCM with hepatocellular carcinoma (HCC), though o … One reason why PVC is so toxic is that it is often mixed with softening chemicals called plasticizers, the most well known variety being phalates. It burns easily. Vinyl Chloride 1. Vinyl chloride … References: cancer.gov, OSHA, IARC, CDC Vinyl Chloride 75-01-4 _____ Hazard Summary . Acute Exposure Guideline Levels. Vinyl chloride is a synthetic, colorless gas. 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